methyl 6-(4-hydroxybut-1-ynyl)pyridine-3-carboxylate - Names and Identifiers
methyl 6-(4-hydroxybut-1-ynyl)pyridine-3-carboxylate - Introduction
methyl 6-(4-hydroxybut-1-ynyl)pyridine-3-carboxylate is an organic synthetic compound with the molecular formula C12H11NO3.
Nature:
1. Appearance: yellow to orange solid.
2. Melting Point: about 50-55 ° C.
3. Solubility: Soluble in ethanol, methanol and chloroform, insoluble in water.
Use:
1. Chemical reagents: as intermediates in organic synthesis, used in the synthesis of other compounds.
2. Drug development: as the structural basis of drug molecules, used to develop and study new drugs.
Method:
methyl 6-(4-hydroxybut-1-ynyl)pyridine-3-carboxylate can be synthesized by the following steps:
1. Benzyl hydroxybutynol reacts with pyridine-3-carboxylic acid to generate 6-(4-hydroxybut-1-ynyl) pyridine-3-carboxylic acid.
2. The synthesized 6-(4-hydroxybut-1-ynyl) pyridine-3-carboxylic acid is reacted with methanol to generate the target product.
Safety Information:
1. methyl 6-(4-hydroxybut-1-ynyl)pyridine-3-carboxylate should be stored in a dry, well-ventilated place, away from fire and flammable materials.
2. During operation, appropriate personal protective equipment, such as gloves, glasses and laboratory coats, should be worn to prevent direct contact and inhalation.
3. Before use, the safety data sheet of the compound should be reviewed and operated in accordance with the operating procedures and laboratory standard operating procedures.
4. If there is discomfort or skin redness, should immediately stop using, and timely medical treatment.
Last Update：2024-04-09 02:00:52